Registration and Regulation of Pesticides

The service allows applications to be submitted for the various stages of authorisation and registration of plant protection products (PPPs - pesticides), and provides information on the authorisation processes.

  • The use and sale of pesticides for plant protection as well as the import of pesticides to Israel are subject to prior authorisation and registration.
  • Only after licensing and registration can applications be submitted to import a product that is not manufactured in Israel.

For your convenience - we have grouped the main steps and processes for registering and licensing pesticides - 

  1. The steps for registering and licensing a pesticide and special processes
  2. Committee for obtaining an experiment permit for the product
  3.  Biological Committee (Efficacy Committee)
  4. Discussion in a Toxicological Committee (Inter-Ministerial Committee)
  5. Determination of pre-harvest interval (PHI) and maximum residue level (MRL) 
  6. Approval of the product label
  7. Registration of a product, renewal or cancellation of a registration certificate
  8. Special authorisation
  9. Registration and approval of products for organic farming
  10. Special permits for substances prohibited for free sale (particularly toxic or harmful to the environment)
     
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  •  The process of registering and licensing a product includes a field trial, which is performed according to rules that allow statistical analysis of the test results, at the end of the process. 
  • Based on these results, approval or rejection of the product's efficacy in eradicating the lesion (pests and diseases), and the product's safety for agricultural cultivation, shall be determined.
  • In order to conduct experiments with a new product, the approval of the Director of Plant Protection and Inspection Services shall be obtained. 
  • Details about the process of conducting the experiment can be found in Chapter 2 of the procedure - committee for approval of execution.

What needs to be attached to the application

Submitting the Application

An application form for conducting experiments (Section 2.4 in Chapter 2 - Committee for Approval of Conducting Field Experiments) shall be submitted.

How to submit the application

An application form for conducting experiments shall be filled out (Section 2.4 in Chapter 2 - Committee for Approval of Conducting Field Experiments), attach the detailed documents in chapter 2 of the procedure - a committee for approval of conducting field experiments and submit the number of copies requested, in accordance with the requirement of the field of registration and licensing. 

  • The forms and documents shall be conveyed during reception hours by prior arrangement by calling (03) 968-1542 or (03) 968-1505, at the offices of the Division of Registration and Authorisation of Pesticides, Plant Protection and Inspection Services, Ministry of Agriculture and Food Security, Maccabim Road, Rishon Lezion.

Continuation Handling of the Application

  • Validity of permits for conducting experiments - two years.
  • An experiment permit can be renewed for up to 5 years.
  • The approved experimental products shall be published on the Plant Protection and Inspection Services website
  • After receiving approval for the trial, the trial phase shall begin. 
  • After the testing phase, one can proceed to the discussion phase in the biological committee (efficacy committee)

The Cost of the Service and Payment

  • If an experiment permit is received, the permit shall be sent along with a fee payment voucher. 
  • The fee can be paid in the following ways:
    • Through the government payment website - a permit to conduct experiments on the product or through the treasurers of the Plant Protection Department by phone at (03) 968-1506 or (03) 968-1444 between the hours 09:00 and 15:00

Licensing of biotic products

  • Biotic products are plant protection products that contain a biotic factor (bacterium, virus, yeast, fungus, etc.).
  • A positive opinion / recommendation of an expert from the Plant Protection and Inspection Services shall also be attached as a necessary condition for obtaining an experiment permit on the product, according to Chapter 2 Section 2.2 of the procedure - Issuing a permit to conduct experiments on the product - Track B
  • The rest of the registration steps shall be taken as described in the procedure.
  • To receive complete information, contact Suha Nasser, Head of Pesticide Registration and Licensing Division at the following email address: [email protected]
     

 

 

 

 

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(1) A committee of experts advising the Director of the Plant Protection and Inspection Services, discusses the evidence based on field trials and proving the efficacy of the pesticide and the safety of the product in any combination of lesion and growth.

The details of the criteria for submitting an efficiency file in Chapter 3 of the Procedure - Efficiency Committee 
 

 

      The documents that shall be attached are intended to complete the information required to prove the efficacy of the product -

      • An application letter from the registering company to the members of the Efficacy Committee detailing the submitted application
      • Contents of the application and documents
      •  A summary table of the works included in the dossier. This table shall serve as a map of the process and shall allow a broad view of how to examine the product in the various growths and lesions.
        • Do not include in the table information that is not relevant for the examination of the case.
      • The experiment permit is signed by the Director of Plant Protection and Inspection Services.
      • Previous letters and the collection of summaries (protocols) of all previous meetings, if held, where decisions were carried out regarding the product in question.
      • Label proposal (initial version) in which the following shall be stated:
        • General information about the product
        • In each lesion-growth combination, the dosage of the product (amount per acre - grams or cubic centimeters) or its concentration in the application solution is to be specified.
        • The phenological stage of the cultural growth and the stage of development of the lesion in which the product should be applied
        • The method of application, the volume of the spray and the times of treatment
        • The degree of phytotoxicity of the product, if any 
        • Influential climatic conditions
        • The relevant combinations of the proposed product with other products already registered for the same crop (if the company wishes to do so). These combinations shall appear in the label proposal, provided they have been practically tested and reported in the results file as detailed below.
        • The effect of the product on natural enemies, fish, honey bees and other beneficial insects and every relevant detail for optimal use of the product.
        • A negative side effect, if present, such as a delay in plant development
        • The recommended use of the product in order to postpone or prevent the development of resistance
        • Relevant instructions and warnings such as frequency of application of the product, residues, permitted crops in the cycle and special treatments required.
        • Special instructions for preparing the product for application, if any.
      • General information about the product received from the manufacturing company, which shall include the label wording offered by the manufacturing company in English, or a translated label (Specimen Label) and labels from other countries where the product is registered (if any). Information from the manufacturing company that is not in English, shall be translated into English or Hebrew. The names of the countries where the active ingredient and product are registered shall be stated. 
      • Reports of conducting field experiments proving the efficacy of the product according to the instructions detailed in Appendix 3
      • Reports on the product's safety tests, as detailed in section 5. The double dose tested in a field trial shall be considered a safety test.

      An application form for registration to the Efficiency Committee shall be filled out Section 3.12 -Chapter 3 of the Procedure- Efficiency Committee (products).

      • The forms and documents shall be brought during reception hours by prior arrangement by calling (03) 968-1542 or (03) 968-1505, to the offices of the Division of Registration and Licensing of Pesticides, the Plant Protection and Inspection Services, Ministry of Agriculture and Food Security, Maccabim Road, Rishon Lezion.
      • It is the company's responsibility to submit the complete file to all committee members no later than 21 days before the hearing
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      The Inter-Ministerial Toxicological Committee discusses the safety of the product for man, animal, and the environment.

      Who can submit an application for a discussion in the committee

      • Discussion in the committee is conditional on the biological committee's recommendation for the use of the product.  

      How do you submit a request for committee discussion

      Required documents and application submission

      • A copy of the protocol of the Efficacy Committee and the Committee's approval shall be forwarded to the Toxicological Committee.
      • In addition, a digital copy of the protocol and the certificate shall be submitted on a digital memory stick.

      The working procedures of the committee

      Authorizing procedure for generic products (Me-Too)

      • The Me Too product (generic product) is a product that contains the same technical material as the registered product
      • A certificate of equivalency proof shall be attached to the toxicological dossier (proof that the product contains a technical substance that is essentially identical to a technical substance in a registered pesticide)
      • For complete information, refer to Chapter 4 Section 4.3 of the Procedure
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      Determination of pre-harvest interval (PHI) and maximum residue level (MRL)

      • Determining the pre harvest interval  (PHI) and maximum residues level (MRL)  in edible crops are based on data from the decay curves of the products, which can be carried out in the laboratories of the Plant Protection and Inspection Services or in another recognized laboratory.
      • The performance of the decay curves is conditional on the prior approval and coordination of the field experiment program with the Chemistry Department.
      • The process of determining MRL values and PHI is detailed in the procedure for submitting an application to determine pre harvest intervals and maximum residue levels of pesticides in agricultural products found in Chapter 5- Section 5.1 to the procedure
         

      What should be attached to the application for determining the PHI

      A dossier shall be submitted to the Licensing Division that includes:
      A.    Label proposal in accordance with the approval of the Efficacy Committee and the Inter-Ministerial Committee
      B.    Efficiency Committee protocol in which a specific crop was discussed
      D.    Results report of the laboratory for pesticide residues at the Plant Protection Services or a recognized laboratory acting on behalf of the Plant Protection Services to perform decay curves. 

      Submitting the Application

      The dossier (one printed copy) shall be submitted to Mrs. Suha Nasser, Director of Pesticide Registration and Licensing Division.

      Handling the Application

      • The discussion of the case shall take place in the presence of representatives of the Ministry of Health and Ministry of Agriculture. 
      • After the discussion - the decision shall be sent to the registering company. 

      More information can be obtained at Public Health Regulations (Food) (Pesticide Residues) 5778 - 2017 
      Clarifications and highlights for verifying waiting days in products

       

       

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      Defined by the Plant Protection Regulations (Arrangement of Import and Sale of Chemical Products) 5755 - 1994. 
      The label is approved by the Pesticides Authorisation and Registration Division, Department A (Chemistry and Pesticides).

      How to submit the label for approval

      The label shall be sent by e-mail to: [email protected]

      In order to add new growths or lesions to the label of a registered pesticide, a process that includes:

      1. Efficacy Committee
      2. Determination of MRL values - (Maximum Residue Limits) 
         
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      Details on how to register a product, renew a registration certificate and cancel a registration certificate

      For a product approved by the committees, a registration certificate shall be issued after paying the two fees: An application for product registration fee and a product registration fee. The payment shall be made through the government payment website or through the treasury department by phone at (03) 968-1506 or (03) 968-1444 between the hours 09:00 to 15:00

      • The product shall be identified with the registration number of the Plant Protection and Inspection Services.

      What should be attached to the registration application

      • Commercial label
      • Confirmation of payment, application for registration of a product and also a fee for registration of a product
      • Application form for registration of the product (Chapter 7 Section 7.3 of the procedure)
      • Material Safety Data Sheet (MSDS)
      • Please note, herbicide labels also require approval. For instructions please contact our contact person at [email protected]

      The cost of the service and payment

      Payment can be made in the following two ways:

      How to submit the application

       The documents required for the field of authorisation and registration shall be submitted to the Chemistry Department, Plant Protection and Inspection Services, by e-mail to the address: [email protected]
       

      Renewal of the registration certificate is carried out once every 6 years, with the exception of registration certificates for products for organic agriculture which is carried out once every 3 years.

      • Those who wish to renew a registered pesticide product, as the first step, shall submit the following documents to a product laboratory:
      • Form for bringing a product for license renewal (chapter 11, section 11.5 of the procedure) – shall be printed and filled out and attached to the form:
        • Samples of the product
        • Technical material
        • An analytical standard accompanied by appropriate documents
        • Form for bringing samples to the laboratory (permit from the laboratory for pesticides)
      • Delivery of the form and all the samples to a product laboratory, in coordination with Mrs. Carmela Fickler by phone at (03) 968-1557 or by email: [email protected]
      • As part of the second step, an application for renewing an authorize certificate shall be submitted and the following documents shall be attached:
        • Updated label
        • Material Safety Data Sheet (MSDS)
        • Product laboratory approval - after the first stage
        • Application form for renewing a license certificate (Chapter 7, Section 7.3 of the procedure)
        • Confirmation of payment of the authorize renewal fee

      Submitting the Application

      The documents required for the authorising field shall be submitted two months before the certificate expires, by e-mail to the following address: [email protected].
       

       

       To cancel the registration certificate of a product that is on the list of approved products, the company holding the registration certificate shall contact the Division of Pesticide Registration and Authorization for instructions, by e-mail at the address: [email protected] 

      This service allows companies registering pesticides products to report the composition of a registered product

      Required Attachments

      • A full composition (100%) of the product must be specified, including inactive ingredients

      • Attach the Manufacturer’s Declaration of Product Composition

      The service is provided free of charge

      How to Apply

      Complete the online form, attach the Manufacturer’s Declaration of Product Composition, and submit.

       

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      Ready to use products shall be registered according to chapter 8, section 8.1 of the procedure

       

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      The Plant Protection and Inspection Services are authorised for the approval and registering of products recognized for use in organic agriculture.

      Registration of a pesticide for organic agriculture is conditional upon registration according to the regulations for registration of products for conventional agriculture

      Compliance testing is carried out by the Advisory Committee to the Director of Plant Protection and Inspection Services, in accordance with the Regulations for Regulating Organic

      Produce (Products for use in the Production of Organic Plant-Based Produce), 5768 - 2008 compared to the Israeli standard for fresh and processed organic produce of plant origin, and Council Regulation No. 2092/91 EEC.

      All inputs for organic agriculture (nutrients, plant protection materials and auxiliary materials for the organic food industry) are tested in accordance with the requirements of the standard.
       

      Steps for approval of products for organic farming

      Cases to the Committee for the Approval of Products for Organic Agriculture shall be submitted on two dates:

      1. Phase of proof of suitability for organic farming according to the Israeli standard or according to the NOP standard.
      2. Efficacy or safety proof stage in cultivation.

        What needs to be attached to the application

        1. Letter of application to committee members
        2. Contents
        3. Check list
        4. The composition in which active and inactive substances are listed with the indication of the CAS numbers of all the components of the product
        5. The identity of the substance and its components
        6. Production method
        7. Certification (Quality Assurance) certificate of the manufacturer for the production of pesticides 
        8. If the producer is registered for organic agriculture globally, a document proving the registration shall be submitted
        9. MSDS of the product
        10. MSDS of all the ingredients of the product
        11. Label proposal
          Products containing an animal component shall be approved in advance by the Veterinary Services at the Ministry of Agriculture and Food Security.

        Submitting the Application

        • The forms and documents shall be brought during reception hours by prior arrangement by calling (03) 968-1542 or (03) 968-1505, to the offices of the Pesticide Registration and Authorization Division, Plant Protection and Inspection Services Building, Ministry of Agriculture and food Security
           

         

        • The Division of Registration and Authorisation of Pesticides grants special permits for products that cannot be freely sold.
        • These restrictions stem from two main reasons:
          1. Are particularly toxic
          2. Have the potential of harming the environment 

        The special permit allows limited purchase and use of pesticides.

        Rosh-80

        The product is limited, to obtain a permit an online application shall be submitted.
        For questions, please contact Dr. Yoav Motro at [email protected]. 

        Methyl bromide in quarantine uses

        For certified exterminators only, in order to obtain a permit, please contact Mr. Uri Pearl by email: [email protected] or by phone at (03) 968-1510

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        Please note, if there is any difference or conflict between the information on this page and the law, the provisions of the law will apply.

        Ministry of Agriculture and Food Security

        Plant Protection and Inspection Services
        Fax: 03-9681500

        Service Center